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半侧颜面短小畸形的理解与治疗的当前概念

Current concepts in the understanding and management of hemifacial microsomia.

作者信息

Cousley R R, Calvert M L

机构信息

Department of Orthodontics, Guy's Hospital, London, UK.

出版信息

Br J Plast Surg. 1997 Oct;50(7):536-51. doi: 10.1016/s0007-1226(97)91303-5.

Abstract

Hemifacial microsomia (HFM) is a complex congenital condition. This review discusses recent research findings which affect all aspects of HFM, and addresses some prevailing misconceptions. Firstly, the broad phenotype is outlined, with an emphasis on the facial anomalies which are important for diagnosis, classification and treatment. The range of HFM anomalies and their possible embryology also account for the varied terms used in the literature. In addition, consideration of causation helps to shape our understanding of HFM as a clinical entity. Aetiology is described with particular emphasis on the involvement of genetic factors, although at present this is largely hypothetical. Finally, the principles of HFM management are reviewed. Attention is given to the integrated planning and team approach necessary to treat such patients. In addition, the possible attributes of new treatments, such as distraction osteogenesis, are highlighted.

摘要

半侧颜面短小畸形(HFM)是一种复杂的先天性疾病。本综述讨论了影响HFM各个方面的最新研究结果,并纠正了一些普遍存在的误解。首先,概述了广泛的表型,重点关注对诊断、分类和治疗至关重要的面部异常。HFM异常的范围及其可能的胚胎学也解释了文献中使用的各种术语。此外,对病因的思考有助于我们将HFM理解为一种临床实体。描述了病因,特别强调了遗传因素的作用,尽管目前这在很大程度上是假设性的。最后,回顾了HFM的治疗原则。关注了治疗此类患者所需的综合规划和团队协作方法。此外,还强调了新治疗方法(如牵张成骨术)可能具有的特性。

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