Tabushi K, Itoh S, Sakura M, Kato S, Kazumoto T, Nakamura Y, Iinuma T A, Arai T, Obata Y
Nagoya University School of Health Sciences.
Nihon Igaku Hoshasen Gakkai Zasshi. 1997 Nov;57(13):871-6.
Stage III carcinoma of the uterine cervix is occasionally accompanied by tumor infiltration of the vaginal wall. Currently, the vaginal wall has to be irradiated in the same manner as the uterine cervix. The authors have developed a system for determining the optimal irradiation conditions for treating the two regions, uterine cervix and vaginal wall, at the same time. A comparison of two methods is shown in simulation, and then a clinical case is reported. The first method consists of two treatment plans, one for the uterine cervix without tumor infiltration of the vaginal wall, and the other for the vaginal wall without carcinoma of the uterine cervix. The second, newly developed method considers the two regions together. Irradiation times of ovoid sources obtained with the second method are 15-25% less than those of the first method. Isodose curves obtained with the two methods are very different, and thus the uterine cervix and vaginal wall must be considered together in order to determine irradiation conditions.
III期子宫颈癌偶尔伴有阴道壁肿瘤浸润。目前，阴道壁必须与子宫颈以相同方式进行照射。作者开发了一种系统，用于同时确定治疗子宫颈和阴道壁这两个区域的最佳照射条件。在模拟中展示了两种方法的比较，然后报告了一个临床病例。第一种方法包括两个治疗计划，一个用于无阴道壁肿瘤浸润的子宫颈，另一个用于无子宫颈癌的阴道壁。第二种新开发的方法将这两个区域一起考虑。用第二种方法获得的卵形源照射时间比第一种方法少15% - 25%。用这两种方法获得的等剂量曲线非常不同，因此为了确定照射条件，必须将子宫颈和阴道壁一起考虑。
