Inoue Y, Yozu R, Mitsumaru A, Ueda T, Kawada S
Department of Surgery, Keio University School of Medicine, Tokyo, Japan.
Artif Organs. 1997 Dec;21(12):1303-5. doi: 10.1111/j.1525-1594.1997.tb00494.x.
Our goal was to determine the feasibility of video-assisted cardioscopic closure of atrial septal defect (ASD) without cardiopulmonary bypass using a staple catheter device and guiding catheter in an experimental setting. An artificial linear atrial septal defect (AASD) was created in 7 swine under video-assisted cardioscopic view, and staple closure was attempted at the AASD with a stapler inserted through a trocar guiding catheter via the right atrium under median sternotomy. The staple device was successfully and safely anchored in 4 animals. The whole process of stapling could be monitored by cardioscope and by post mortem macroscopic examination. In conclusion, although the size and flexibility of the stapler and the guiding catheter must be improved, our results demonstrate that there is a strong potential for video-assisted staple closure of ASD using this novel technique, which could contribute to the reduction of the number of open heart operations and thereby iatrogenic morbidity.
我们的目标是在实验环境中，确定使用吻合器导管装置和引导导管在非体外循环下通过视频辅助心脏镜闭合房间隔缺损（ASD）的可行性。在视频辅助心脏镜视野下，对7头猪制造人工线性房间隔缺损（AASD），并在胸骨正中切开术下经右心房通过套管引导导管插入吻合器，尝试对AASD进行吻合器闭合。吻合器装置在4只动物中成功且安全地固定。吻合过程可通过心脏镜和死后大体检查进行监测。总之，尽管吻合器和引导导管的尺寸及灵活性仍需改进，但我们的结果表明，使用这种新技术通过视频辅助吻合器闭合ASD具有很大潜力，这有助于减少心脏直视手术的数量，从而降低医源性发病率。
