Baevskiĭ R M, Nikulina G A
Gosudarstvennyĭ nauchnyĭ tsentr RF "Institut mediko-biologicheskikh problem".
Aviakosm Ekolog Med. 1997;31(4):61-4.
Adjusting reactions of human body were evaluated using mathematical analysis of the cardiac rhythm. Variability of cardiac intervals was reduced in consequence of an elevation of sympathetic tone within the autonomous nervous system. Analyzed were diurnal arrays of cardiac intervals derived from Holter monitoring data. Pulse rate and standard deviation of the cardiac interval length were calculated for each of the 5-minute periods of recording. These data were used to calculate values of the parameters per an hour, 8 hours, and 24 hours. The analysis revealed that generally the body stress-reaction to prolonged isolation consists of increased strain of regulating systems in an effort to mobilize functional reserves. Depending on individual characteristics and functional reserves, the regulating systems become overstrained at some time-point and higher level regulators may be involved in adaptation. Criteria of overstrain include exaggerated pulse rate versus rising standard deviation. Combination of these shifts during morning and night hours should be qualified as least favorable. Test-subject 003, in whom regulation overstrain has been never observed in the experiment, was distinguished by the largest functional reserve.
通过对心律进行数学分析来评估人体的适应性反应。自主神经系统内交感神经张力升高导致心搏间期变异性降低。分析了来自动态心电图监测数据的昼夜心搏间期序列。对记录的每5分钟时段计算心率和心搏间期长度的标准差。这些数据用于计算每小时、8小时和24小时的参数值。分析表明，一般来说，身体对长期隔离的应激反应包括调节系统的应变增加，以努力调动功能储备。根据个体特征和功能储备，调节系统在某个时间点会过度紧张，更高层次的调节因子可能参与适应过程。过度紧张的标准包括心率过高与标准差上升。早晚时段这些变化的组合应被视为最不利的情况。受试者003在实验中从未观察到调节过度紧张，其功能储备最大。
