Sadikova O N, Glozman Zh M
Zh Nevrol Psikhiatr Im S S Korsakova. 1997;97(10):40-4.
There were observed of 88 patients with Parkinson's disease. According to data of computer tomography 3 groups of patients were determined: with external type of cerebral atrophy (CA) mainly, with internal type of CA mainly and combined type too. Neuropsychologic study revealed differences among CA types both in degree of manifestation and in character of alteration of high mental functions. Together with neuropsychologic symptoms of the damages of mediobasal structures which were quite characteristic for this disease, there were also revealed the damages of convex cortical areas of frontal, parietal and temporal lobes. Pathologic inertia, inactivity of remembering and impairment of the processes of generalization were found more frequently at internal type of CA. Meanwhile at external CA type both difficulties of learning and disorders of motor programs' control were observed. The obvious correlations were also established between the degree of cognitive alterations and a presence of CA. Moreover, CA type had certain influence mainly on the structure but not on the manifestation of the cognitive disorders.
对88例帕金森病患者进行了观察。根据计算机断层扫描数据,确定了3组患者:主要为脑萎缩(CA)的外部类型、主要为CA的内部类型以及混合型。神经心理学研究发现,CA类型在高级心理功能改变的表现程度和特征方面均存在差异。除了该疾病典型的中基底结构损伤的神经心理学症状外,还发现额叶、顶叶和颞叶凸面皮质区域存在损伤。在CA的内部类型中,病理惰性、记忆不活跃和概括过程受损更为常见。同时,在CA的外部类型中,观察到学习困难和运动程序控制障碍。认知改变程度与CA的存在之间也建立了明显的相关性。此外,CA类型主要对认知障碍的结构而非表现有一定影响。