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[连续性动静脉血液滤过在休克和多器官功能不全综合征患者治疗中的应用]

[Continuous arteriovenous hemofiltration in the management of patients with shock and multiorgan insufficiency syndrome].

作者信息

Wajda Z, Wysocki T

机构信息

II Katedry i Kliniki Chirurgii Ogólnej, Gastroenterologicznej i Endokrynologicznej Akademii Medycznej w Gdańsku.

出版信息

Wiad Lek. 1997;50 Suppl 1 Pt 2:190-7.

PMID:9424873
Abstract

Spontaneous continuous arterio-venous hemofiltration (CAVH) is a blood purification system based on blood filtration through capillary hemofilters without pumps, using the arterio-venous pressure gradient for blood perfusion. In 2-nd Department of Surgery of Medical University of Gdańsk in the years 1989-1996 we introduced CAVH 13 times in 6 women and 7 men, aged from 17 till 79 years. We used this technique to maintain fluid balance in anuric patients needing parenteral fluids. Due to circulatory and respiratory insufficiency all patients needed catecholamines infusion and controlled respiration. In 7 patients acute renal failure was caused by septic shock and in 6 patients by shock after severe multiorgan injuries. The CAVH therapy lasted from 3 till 16 days. The stabilisation of hemodynamic and renal parameters was observed in all patients. 3 patients died of cranio-cerebral injuries and 2 due to longlasting septic shock induced by necrotic pancreatitis. In all patients CAVH was required to remove the excess water given as carrier in total parenteral nutrition. Experience with 13 cases has shown the CAVH technique, to be particularly useful in patients with vascular instability or severe fluid overload. The above method which needs no technical investment is simple to handle.

摘要

自发性连续性动静脉血液滤过(CAVH)是一种血液净化系统,它基于通过无泵的毛细血管血液滤过器进行血液滤过,利用动静脉压力梯度进行血液灌注。1989年至1996年期间,在格但斯克医科大学第二外科,我们对6名女性和7名男性(年龄在17岁至79岁之间)进行了13次CAVH治疗。我们使用该技术来维持需要胃肠外补液的无尿患者的液体平衡。由于循环和呼吸功能不全,所有患者都需要输注儿茶酚胺并进行控制呼吸。7例患者的急性肾衰竭由感染性休克引起,6例患者由严重多器官损伤后的休克引起。CAVH治疗持续了3至16天。所有患者均观察到血流动力学和肾脏参数的稳定。3例患者死于颅脑损伤,2例死于坏死性胰腺炎引起的长期感染性休克。在所有患者中,均需要CAVH来清除全胃肠外营养中作为载体给予的多余水分。13例病例的经验表明,CAVH技术在血管不稳定或严重液体超负荷的患者中特别有用。上述方法无需技术投入,操作简单。

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[Continuous arteriovenous hemofiltration in the management of patients with shock and multiorgan insufficiency syndrome].[连续性动静脉血液滤过在休克和多器官功能不全综合征患者治疗中的应用]
Wiad Lek. 1997;50 Suppl 1 Pt 2:190-7.
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