Bobrzyński A, Gedliczka O, Bielański W, Stachura J, Konturek S, Budzyński A
II Katedry i Kliniki Chirurgii Ogólnej, Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie.
Wiad Lek. 1997;50 Suppl 1 Pt 2:345-9.
Microstructural, endo- and exocrine changes in gastric mucosa of Non-Ulcer Dyspepsia patients with H. pylori infection in the course of eradication has been studied. Before, during and after anti H. pylori therapy plasma gastrin and somatostatin levels, EGF and somatostatin concentration in gastric juice and basal and pentagastrin stimulated gastric acid secretion were measured. Moreover microstructure of gastric mucosa specimens has been studied. Maximal Acid Output initially higher in NUD patients than in healthy volunteers increased slightly in the course of eradication. Plasma gastrin decreased while EGF and somatostatin concentration in gastric juice increased. After treatment the ratio of patients with pronounced features (activity) of gastritis was significantly reduced.
对根除幽门螺杆菌感染过程中幽门螺杆菌感染的非溃疡性消化不良患者胃黏膜的微观结构、内分泌和外分泌变化进行了研究。在抗幽门螺杆菌治疗前、治疗期间和治疗后，测量了血浆胃泌素和生长抑素水平、胃液中表皮生长因子（EGF）和生长抑素浓度以及基础胃酸分泌和五肽胃泌素刺激的胃酸分泌。此外，还研究了胃黏膜标本的微观结构。非溃疡性消化不良患者的最大胃酸分泌量最初高于健康志愿者，在根除过程中略有增加。血浆胃泌素水平下降，而胃液中表皮生长因子和生长抑素浓度增加。治疗后，具有明显胃炎特征（活动度）的患者比例显著降低。
