患有类风湿性关节炎的煤矿工人的血清免疫球蛋白、类风湿因子和尘肺病

Serum immunoglobulins, rheumatoid factor, and pneumoconiosis in coal miners with rheumatoid arthritis.

作者信息

Benedek T G, Zawadzki Z A, Medsger T A

出版信息

Arthritis Rheum. 1976 Jul-Aug;19(4):731-6. doi: 10.1002/1529-0131(197607/08)19:4<731::aid-art1780190412>3.0.co;2-w.

DOI:10.1002/1529-0131(197607/08)19:4<731::aid-art1780190412>3.0.co;2-w

Abstract

The occurrence and severity of pneumoconiosis were studied in 100 coal miners with rheumatoid arthritis (RA) and compared to findings in a geographically relevant survey of coal workers' pneumoconiosis. Contrary to European reports, miners with RA were not found to have an excessive frequency or severity of pneumoconiosis. In 55 of these men, serum immunoglobulin levels and rheumatoid factor were compared with data from matched RA patients with no history of silica exposure. The immunochemical results were unrelated to the stage of pneumoconiosis, nor did they differ from those in the control group.

摘要

对100名患有类风湿性关节炎（RA）的煤矿工人的尘肺病发生情况和严重程度进行了研究，并与一项在地理位置相关的煤矿工人尘肺病调查结果进行了比较。与欧洲的报告相反，未发现患有RA的矿工尘肺病的发病率或严重程度过高。在其中55名男性中，将血清免疫球蛋白水平和类风湿因子与无二氧化硅接触史的匹配RA患者的数据进行了比较。免疫化学结果与尘肺病阶段无关，也与对照组的结果没有差异。