Morris K, Bharucha C
Northern Ireland Blood Transfusion Service (NIBTS), Belfast City Hospital Complex.
Eur J Med Res. 1997 Dec 31;2(12):523-6.
In a retrospective analysis two methods for preventing platelet transfusion reactions are compared. The first group of patients received platelets filtered in the hospital blood bank and were subsequently given filtered and washed platelets if they developed reactions. The second group received platelets filtered at the bedside. In the group receiving platelets filtered in the hospital blood bank there was a very low rate of reaction (2/101 = 2%) and no patients receiving filtered and washed platelets (0/91) developed a reaction. In the group receiving platelets filtered at the bedside there was a reaction rate of 19/95 (20%). Further, two of these reactions were categorised as very severe, the patients showing hypotensive collapse. We conclude that filtering platelets in the hospital blood bank is significantly more effective than bedside filtration in preventing platelet transfusion reactions.
在一项回顾性分析中，对两种预防血小板输血反应的方法进行了比较。第一组患者接受在医院血库过滤的血小板，若出现反应则随后给予过滤并洗涤过的血小板。第二组接受在床边过滤的血小板。在接受医院血库过滤血小板的组中，反应率非常低（2/101 = 2%），且接受过滤并洗涤过血小板的患者（0/91）均未出现反应。在接受床边过滤血小板的组中，反应率为19/95（20%）。此外，其中两例反应被归类为非常严重，患者出现低血压性虚脱。我们得出结论，在预防血小板输血反应方面，在医院血库过滤血小板比床边过滤显著更有效。
