Matthews M S, Cohen M, Viglione M, Brown A S
Division of Plastic Surgery, Cooper Hospital/University Medical Center, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, USA.
Plast Reconstr Surg. 1998 Jan;101(1):1-5. doi: 10.1097/00006534-199801000-00001.
Prenatal diagnoses of cleft lip and palate can occur during both routine screening obstetrical ultrasound and high resolution obstetrical ultrasound done for other reasons. The affected family or obstetrician may request prenatal consultation with the plastic surgeon. To define this population, a survey was done of all families who were referred to our cleft program with a prenatal diagnosis of cleft between 1990 and 1994. Of 80 newborn referrals, 13 had a prenatal diagnosis of cleft. These children had a higher incidence of bilateral cleft than our average population (53.8 percent versus 28.7 percent, p < 0.03, chi square test). No isolated cleft palates were identified. Nine families were available for follow-up. Only one-third of the families felt that they had been given adequate information about clefts from their obstetrician or ultrasonographer. All who had prenatal contact with the cleft team felt it was valuable. A review of prenatal diagnosis of cleft is given including limitations. Specific counseling information is discussed.
唇腭裂的产前诊断可在常规产科超声筛查以及因其他原因进行的高分辨率产科超声检查过程中出现。受影响的家庭或产科医生可能会要求与整形外科医生进行产前会诊。为明确这一群体的情况，我们对1990年至1994年间因产前诊断为唇腭裂而被转介至我们唇腭裂治疗项目的所有家庭进行了一项调查。在80例新生儿转诊病例中，有13例产前诊断为唇腭裂。这些儿童双侧唇腭裂的发生率高于我们的总体人群（53.8%对28.7%，p<0.03，卡方检验）。未发现单纯腭裂病例。有9个家庭可供随访。只有三分之一的家庭认为他们从产科医生或超声检查医生那里获得了关于唇腭裂的充分信息。所有在产前与唇腭裂治疗团队接触过的家庭都认为这种接触很有价值。本文对唇腭裂的产前诊断进行了综述，包括其局限性。还讨论了具体的咨询信息。
