松果体区节细胞胶质瘤：病例报告及文献复习
Ganglioglioma of the pineal region: case report and review of the literature.
作者信息
Faillot T, Sichez J P, Capelle L, Kujas M, Fohanno D
机构信息
Department of Neurosurgery, Hôpital de la Pitié, Paris, France.
出版信息
Surg Neurol. 1998 Jan;49(1):104-7; discussion 107-8. doi: 10.1016/s0090-3019(97)00302-9.
BACKGROUND
Ganglioglioma is a lesion rarely encountered in the pineal region. Only six cases have been published to our knowledge.
METHODS AND RESULTS
We present the case of a 38-year-old male suffering from a pineal ganglioglioma that was totally removed by surgery. Histological diagnosis was made by light microscopy using immunostaining for synaptophysin. We review the few radiological and pathological data available in the literature concerning this very rare lesion for which surgery alone provides excellent results.
CONCLUSION
The possibility of long term remission obtained by surgery alone and the lack of specificity of clinical and radiological features of ganglioglioma are additional reasons for an aggressive surgical management of pineal tumors when tumor markers and cytopathological examination of the cerebrospinal fluid are not contributive.
背景
松果体区神经节胶质瘤是一种罕见的病变。据我们所知，仅发表过6例相关病例。
方法与结果
我们报告了一例38岁男性松果体神经节胶质瘤患者，该肿瘤经手术完全切除。通过对突触素进行免疫染色，利用光学显微镜进行组织学诊断。我们回顾了文献中关于这种极为罕见病变的少量影像学和病理学数据，对于该病变，仅手术就能取得良好效果。
结论
仅通过手术就能实现长期缓解，以及神经节胶质瘤临床和影像学特征缺乏特异性，这些都是在肿瘤标志物和脑脊液细胞病理学检查无帮助时，对松果体肿瘤采取积极手术治疗的额外原因。
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