Suppr超能文献

孕20周后紧急宫颈环扎术:对34例患者6年实践的回顾性研究

Emergency cervical cerclage after 20 weeks' gestation: a retrospective study of 6 years' practice in 34 cases.

作者信息

Benifla J L, Goffinet F, Darai E, Proust A, De Crepy A, Madelenat P

机构信息

Service de Gynécologie Obstétrique, Hôpital Bichat, Paris, France.

出版信息

Fetal Diagn Ther. 1997 Sep-Oct;12(5):274-8. doi: 10.1159/000264484.

Abstract

The aim of this study was to evaluate the outcome of late emergency cervical cerclage, after 20 weeks' gestational age (GA). This report describes a retrospective study from January 1, 1988 to December 31, 1993, of 34 patients with intact membranes who required emergency cervical cerclage after 20 weeks of GA, on observing significant cervical changes such as 'cervix dilated at least 2 cm and bulging membranes', in the Department of Obstetrics and Gynecology (Bichat-Claude Bernard Public Hospital, Paris, France). Eight patients were primigestae, and 3 had twin pregnancies. After 48 h resting under tocolysis infusion, emergency cervical cerclage (MacDonald technique) was performed with general anesthesia and prophylactic antibiotic administration. Out of 34 patients, 19 (73.1%) had a past history of one or more previous obstetrical events capable of causing cervical incompetence (CI). Mean duration of pregnancy at emergency cervical cerclage was 22.1 weeks of GA, and at delivery was 35.7 weeks of GA. The mean prolongation of pregnancy obtained was 13.9 weeks. There was a significant negative linear relationship between term at time of cerclage and the prolongation of pregnancy. In this series, 6 patients (17.6%) delivered before 28 weeks of GA, and 6 further patients (17.6%) delivered between 28 and 37 weeks of GA. Chorioamnionitis was observed in 5 cases (14.8%). Overall the neonatal survival rate was 86.5%, with 5 deaths among a total of 37 newborn. Two fetuses died in utero as a consequence of chorioamnionitis, 2 twins died shortly after birth at 24 weeks of GA, and 1 died after failure of emergency cervical cerclage (peroperative rupture of membrane). Out of 32 alive newborn, 7 were admitted to intensive care and were followed up at age 1 year with no signs of major handicap. On observing significant cervical changes with bulging membrane through an open cervix after 20 weeks of GA, an 'aggressive' multifactorial approach including cervical cerclage is legitimate and is associated with a satisfactory fetal survival rate with a minimum of maternal complications. However, in the absence of a controlled study and regardless of the major ethical problems this might entail, these beneficial effects described cannot be considered as proved.

摘要

本研究的目的是评估孕20周后晚期紧急宫颈环扎术的结局。本报告描述了一项回顾性研究,研究对象为1988年1月1日至1993年12月31日期间,法国巴黎比夏-克劳德·贝尔纳公立医院妇产科34例胎膜完整、孕20周后出现“宫颈扩张至少2 cm且胎膜膨出”等明显宫颈变化而需要紧急宫颈环扎术的患者。8例为初产妇,3例为双胎妊娠。在进行48小时的静脉滴注宫缩抑制剂休息后,采用全身麻醉并预防性使用抗生素,实施紧急宫颈环扎术(麦克唐纳技术)。34例患者中,19例(73.1%)有一次或多次既往产科事件史,这些事件可能导致宫颈机能不全(CI)。紧急宫颈环扎术时的平均孕周为22.1周,分娩时的平均孕周为35.7周。获得的平均孕周延长为13.9周。环扎时的孕周与孕周延长之间存在显著的负线性关系。在该系列中,6例(17.6%)在孕28周前分娩,另外6例(17.6%)在孕28至37周之间分娩。观察到5例(14.8%)发生绒毛膜羊膜炎。总体而言,新生儿存活率为86.5%,37例新生儿中有5例死亡。2例胎儿因绒毛膜羊膜炎死于宫内,2例双胎在孕24周出生后不久死亡,1例在紧急宫颈环扎术失败(术中胎膜破裂)后死亡。32例存活新生儿中,7例入住重症监护病房,1岁时随访无重大残疾迹象。在孕20周后通过开放宫颈观察到明显的宫颈变化且胎膜膨出时,包括宫颈环扎术在内的“积极”多因素方法是合理的,并且与令人满意的胎儿存活率相关,同时产妇并发症最少。然而,在缺乏对照研究且无论这可能带来的主要伦理问题的情况下,所描述的这些有益效果不能被视为已得到证实。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验