Boshoff C, Weiss R A
Institute of Cancer Research, Chester Beatty Laboratories, London, UK,
Mol Med Today. 1997 Nov;3(11):488-94. doi: 10.1016/S1357-4310(97)01116-7.
Kaposi's sarcoma is an angiogenic neoplasm composed of endothelial and spindle cells. The enormous increase in Kaposi's sarcoma with HIV infection, and recent discovery that a new human herpesvirus (Kaposi's sarcoma-associated herpesvirus, also called human herpesvirus 8) is present in this tumor, has activated intense interest in the aetiology, epidemiology and pathogenesis of this disease. Today, Kaposi's sarcoma is one of the most frequent neoplasms in men under 50 years old in the USA, and in some African countries it is the most common tumour overall.
卡波西肉瘤是一种由内皮细胞和梭形细胞组成的血管生成性肿瘤。随着艾滋病病毒感染，卡波西肉瘤的发病率大幅上升，并且最近发现一种新的人类疱疹病毒（卡波西肉瘤相关疱疹病毒，也称为人类疱疹病毒8）存在于这种肿瘤中，这引发了人们对该疾病病因、流行病学和发病机制的浓厚兴趣。如今，卡波西肉瘤是美国50岁以下男性中最常见的肿瘤之一，在一些非洲国家，它是总体上最常见的肿瘤。
