Nomura H, Hayashi J, Kajiyama W, Kashiwagi S
Department of General Medicine, Kyushu University Hospital, Fukuoka, Japan.
Fukuoka Igaku Zasshi. 1997 Nov;88(11):345-51.
A total of 2,825 Japanese over 20 years of age living in the Yaeyama District of Okinawa, Japan were investigated in 1983 and 1984 to determine the prevalence and risk factors of liver abnormalities. Obesity index, hepatitis B virus markers, hepatitis C virus marker and serum transaminase were measured and the history of alcohol intake was recorded. People with elevated transaminase levels were assumed to have abnormalities of the liver. The overall prevalence of liver abnormalities was 3.6% and was significantly higher in men than in women (p < 0.001). Logistic regression analysis showed that the strongest predictors of liver abnormalities were alcohol for the men and obesity for the women. Hepatitis B virus was the second most prevalent risk factor in both sexes.
1983年和1984年，对居住在日本冲绳八重山地区的2825名20岁以上的日本人进行了调查，以确定肝脏异常的患病率和危险因素。测量了肥胖指数、乙型肝炎病毒标志物、丙型肝炎病毒标志物和血清转氨酶，并记录了饮酒史。转氨酶水平升高的人被认为存在肝脏异常。肝脏异常的总体患病率为3.6%，男性显著高于女性（p<0.001）。逻辑回归分析表明，肝脏异常的最强预测因素在男性中是饮酒，在女性中是肥胖。乙型肝炎病毒是两性中第二常见的危险因素。
