Gorzalka B B, Whalen R E
Behav Genet. 1976 Jan;6(1):7-15. doi: 10.1007/BF01065674.
Thirty female CD-1 mice, 30 female Swiss-Webster mice, 45 hybrid female mice of the strain SWCD1F1, AND 45 HYBRId female mice of the strain CD1SWF1 were ovariectomized and administered estradiol benzoate once weekly for 6 weeks. Estrogen injections were followed 2 days later by injections of progesterone, dihydroprogesterone (DHP), or oil and the animals were tested for receptivity 7 hr later. Over the six tests, there was a progressive increase in the frequency of lordosis responses in all strains following progesterone treatment. However, lordosis scores varied widely across animals within strains. Following DHP treatment, lordosis frequency was not increased in the Swiss-Webster strain. Females in the other strains did show a progressive increase in lordosis frequency over weeks. The data indicate that the hybrid strains develop the potential to respond to DHP and thus behave like the CD-1 strain, suggesting that sensitivity to DHP is a dominant trait.
30只雌性CD-1小鼠、30只雌性瑞士-韦伯斯特小鼠、45只SWCD1F1品系的杂种雌性小鼠和45只CD1SWF1品系的杂种雌性小鼠接受了卵巢切除术，并每周注射一次苯甲酸雌二醇，持续6周。在雌激素注射2天后，接着注射孕酮、二氢孕酮（DHP）或油，7小时后对动物进行接受性测试。在六次测试中，所有品系在接受孕酮治疗后，脊柱前凸反应的频率都有逐渐增加。然而，各品系内动物的脊柱前凸评分差异很大。在接受DHP治疗后，瑞士-韦伯斯特品系的脊柱前凸频率没有增加。其他品系的雌性在数周内脊柱前凸频率确实有逐渐增加。数据表明，杂种品系产生了对DHP作出反应的潜力，因此表现得与CD-1品系相似，这表明对DHP的敏感性是一个显性性状。
