Takai Y, Seki H, Kinoshita K
Department of Obstetrics and Gynecology, Saitama Medical Center, Kawagoe, Japan.
Int J Gynaecol Obstet. 1997 Nov;59(2):133-7. doi: 10.1016/s0020-7292(97)00203-8.
Pheochromocytoma is a rare disease that may occur during pregnancy. Antenatal diagnosis is essential to improve fetal and maternal mortality and morbidity, but is difficult. A hypertensive crisis was induced by metoclopramide, a widely used anti-emetic, in a pregnant normotensive woman. Biochemical measurements of plasma and urine catecholamines and magnetic resonance imaging (MRI) established the diagnosis of pheochromocytoma. She was medically treated with prazocin and electively delivered by cesarean section simultaneously with tumor resection.
嗜铬细胞瘤是一种可能在孕期发生的罕见疾病。产前诊断对于降低胎儿和母亲的死亡率及发病率至关重要,但颇具难度。一名血压正常的孕妇因使用广泛应用的止吐药甲氧氯普胺诱发了高血压危象。通过血浆和尿液儿茶酚胺的生化检测以及磁共振成像(MRI)确诊为嗜铬细胞瘤。她接受了哌唑嗪药物治疗,并在择期剖宫产的同时进行肿瘤切除。