Graze P R, McGrath P, Washington G C, Royston I
Can J Microbiol. 1976 Jan;22(1):101-4. doi: 10.1139/m76-013.
An electron microscopic study of the morphology of Herpesvirus macaca, a serologically distinct infectious agent isolated from the leukocytes of rhesus monkeys, was performed. WI-38 fibroblast monolayers were infected with the virus and examined 18 days later. The morphology of Herpesvirus macaca was, in general, typical of the herpesvirus group. Enveloped virus particles observed via negative-stain technique had a diameter of 145-155 nm. An inner capsid composed of hexagonal capsomeres had a diameter of 100-110 nm and surrounded a central core. While enveloped forms appeared to be present within the nuclei of infected cells, they were not found in the cytoplasm except within vacuolar structures. Associated changes were found in the morphology of infected cells, including intracytoplasmic myelin figures.
对从恒河猴白细胞中分离出的一种血清学上独特的感染因子——猕猴疱疹病毒的形态进行了电子显微镜研究。用该病毒感染WI - 38成纤维细胞单层，并在18天后进行检查。猕猴疱疹病毒的形态总体上是疱疹病毒组的典型形态。通过负染技术观察到的包膜病毒颗粒直径为145 - 155纳米。由六边形壳粒组成的内衣壳直径为100 - 110纳米，并围绕着一个核心。虽然包膜形式似乎存在于受感染细胞的细胞核内，但除了在液泡结构内，在细胞质中未发现。在受感染细胞的形态中发现了相关变化，包括胞浆内髓鞘样结构。
