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[帕金森病的电休克治疗。三例病例描述]

[Electroconvulsive therapy in Parkinson disease. Description of three cases].

作者信息

Avila A, Sastre F, Cardona X, Maho P, Bello J, Sancho I

机构信息

Servicio de Neurología, Consorci de l'Hospital de la Creu Roja, L'Hospitalet de Llobregat, Barcelona.

出版信息

Neurologia. 1997 Aug-Sep;12(7):313-6.

PMID:9432202
Abstract

Electroconvulsive therapy (ECT) has demonstrated to be useful in psychiatric patients with parkinsonism as well as patients with Parkinson's disease (PD) without associated psychopathology. We prospectively evaluated three patients with PD and major depression in whom ECT proved to be efficacious. These patients experimented a marked improvement measured by the Unified Parkinson's Rating Scale (UPDRS). In two cases the ECT allowed for a reduction in their drug treatment, and in one case complex fluctuations disappeared. In the two patients who continued with ECT fortnightly, the improvement observed inicially has remained. Since ECT has shown a good tolerance, we conclude that this therapy should be considered as an alternative approach for PD patients with a poor answer to conventional treatment.

摘要

电休克治疗(ECT)已被证明对患有帕金森症的精神科患者以及无相关精神病理学症状的帕金森病(PD)患者有用。我们前瞻性地评估了3例患有PD且伴有重度抑郁症的患者,ECT对他们被证明是有效的。这些患者通过统一帕金森病评定量表(UPDRS)测量显示有显著改善。在2例患者中,ECT使他们的药物治疗得以减少,在1例患者中,复杂的波动消失了。在2例继续每两周接受一次ECT治疗的患者中,最初观察到的改善得以维持。由于ECT已显示出良好的耐受性,我们得出结论,对于对传统治疗反应不佳的PD患者,应将这种治疗方法视为一种替代方法。

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