The biochemical effect of auromomycin on bacterial cells.
作者信息
Suzuki H, Nishimura T, Tanaka N
出版信息
J Antibiot (Tokyo). 1979 Jul;32(7):706-10. doi: 10.7164/antibiotics.32.706.
PMID:94325
Abstract
The mechanism of action of auromomycin was studied with intact cells of Bacillus subtilis. The antibiotic exhibited a preferential inhibition of DNA synthesis over RNA and protein syntheses. The strand scission of cellular DNA was induced by the drug, and DNA was degraded into acid-soluble fragments. The results suggested that DNA is the chemoreceptor of auromomycin.
摘要
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