Shubin F N
Zh Mikrobiol Epidemiol Immunobiol. 1997 Sep-Oct(5):22-5.
The plasmid profile of 489 Y. pseudotuberculosis strains, serovar 1b, isolated from patients during 23 outbreaks and in sporadic cases of the disease were studied. As revealed in this study, in foci with the heterogeneous population of Y. pseudotuberculosis, serovar 1b, outbreaks and sporadic cases of the disease were caused by the polyclonal population of the microorganism. The study showed that three types of outbreaks could be differentiated, depending on the clonal characteristics of the microorganism causing these outbreaks and the presence of the dominating clone of the causative agent. Y. pseudotuberculosis infection caused by the combination of several clones of the microorganism was designated as polyclonal infection.
对从23起疫情及散发病例中分离出的489株1b血清型假结核耶尔森菌的质粒图谱进行了研究。如本研究所示,在1b血清型假结核耶尔森菌种群异质性的疫源地中,疾病的暴发和散发病例是由该微生物的多克隆种群引起的。研究表明,根据引起这些疫情的微生物的克隆特征以及病原体优势克隆的存在情况,可以区分出三种类型的疫情。由该微生物的几个克隆组合引起的假结核耶尔森菌感染被称为多克隆感染。