Shubin F N, Sibirtsev Iu T, Rasskazov V A
Zh Mikrobiol Epidemiol Immunobiol. 1985 Dec(12):53-6.
The results obtained in the electrophoretic study of the plasmid spectra of 190 Y. pseudotuberculosis strains, isolated from different sources, in 0.6% agarose gel are presented. 11 types of plasmids differing in their molecular weight have been detected. Plasmids with a molecular weight of 45 MD determine Ca2+ dependence, bacterial virulence for white mice and autoagglutination. The presence of differences in Y. pseudotuberculosis strains of serovars I, III and IV has been established, which is manifested by their differing plasmid spectra. The relationship between the presence of plasmids with a molecular weight of 75 and 45 DM in the strains and the character of pseudotuberculosis morbidity in the population has been demonstrated. The epidemic course of infection correlates with the presence of both these plasmids and the sporadic course of infection, with the presence of the plasmid with a molecular weight of 45 MD only.
本文展示了从不同来源分离出的190株假结核耶尔森氏菌菌株在0.6%琼脂糖凝胶中进行质粒谱电泳研究的结果。已检测到11种分子量不同的质粒。分子量为45 MD的质粒决定了对Ca2+的依赖性、对小白鼠的细菌毒力和自身凝集作用。已确定血清型I、III和IV的假结核耶尔森氏菌菌株存在差异,表现为它们不同的质粒谱。已证明菌株中分子量为75和45 DM的质粒的存在与人群中假结核发病率的特征之间的关系。感染的流行过程与这两种质粒的存在相关,而散发感染过程仅与分子量为45 MD的质粒的存在相关。