Brikman V D, Balakhonov S V, Mironova L P, Aparin G P
Zh Mikrobiol Epidemiol Immunobiol. 1989 Jul(7):3-7.
112 newly isolated clinical cultures of Y. pseudotuberculosis have been studied. The strains have been characterized by the presence of plasmids and pathogenicity signs associated with plasmids. The results of the study have confirmed the decisive role of the plasmid with a molecular weight of 44-48 MD in the virulence of Y. pseudotuberculosis. The plasmid with a molecular weight of 82 MD, previously attributed the role of an epidemic marker, has also been found to be widely spread. Our study has revealed no specific features in the plasmid composition of the strains isolated under the conditions of sporadic and epidemic pseudotuberculosis morbidity. The results of the study of the pathogenicity of isogenic derivatives differing by the presence of pXV indicate that the role of plasmids with molecular weights of 3.8 and 82 MD in this process is not essential in the model systems, traditional for enteroinvasive Yersinia.
对112株新分离的假结核耶尔森氏菌临床培养物进行了研究。这些菌株通过质粒的存在以及与质粒相关的致病性特征进行了表征。研究结果证实了分子量为44 - 48 MD的质粒在假结核耶尔森氏菌毒力中起决定性作用。先前被认为具有流行标记作用的分子量为82 MD的质粒也被发现广泛传播。我们的研究未发现散发性和流行性假结核发病情况下分离菌株的质粒组成有特定特征。对因pXV存在而不同的同基因衍生物致病性的研究结果表明，在肠道侵袭性耶尔森氏菌传统的模型系统中，分子量为3.8和82 MD的质粒在此过程中的作用并非必不可少。
