Eremenko A A, Chaus N I, Levikov D I, Kolomiets V Ia
Anesteziol Reanimatol. 1997 Sep-Oct(5):36-8.
Noninvasive ventilation of the lungs using a mask (NIVLM) was used in 54 patients with hypercapnic (n = 14) and hypoxemic (n = 40) respiratory failure. Respironics (USA) nasal and facial masks were applied. Ventilation regimens were selected individually. Trigger monitored ventilation, intermittent forced ventilation of the lungs, and assisted ventilation with positive expiratory pressure, biphasic positive pressure in the airways, and constant positive pressure in the respiratory contour were used. The efficacy of NIVLM in patients with hypercapnic respiratory failure was 100%. The pCO2 and ETCO2 normalized in all patients both during and after discontinuation of NIVLM. Despite a relatively long period of ventilation (229 +/- 72 min), the patients did not complain of discomfort during the procedure; no complications or individual intolerance of nasal or facial masks were observed. In patients with hypoxemic respiratory failure NIVLM resulted in a decrease of dyspnea, increase of respiratory volume, etc. The detected changes did not disappear after NIVLM was discontinued. Individual tolerance of nasal and facial masks was somewhat worse in this group: patients complained of stuffiness, lack of air, difficult respiration. Six patients (18.2%) developed episodes of psychomotor excitation which required sedative and analgesic therapy. In general, the efficacy of NIVLM was 91%, but resolution of respiratory failure without repeated intubation of the trachea was attained in only 33 patients (87%) with the hypoxemic condition. The mean duration of NIVLM in this group was 464 +/- 47 min. Hence, NIVLM is an effective method for respiratory support in patients with both hypoxemic and hypercapnic respiratory failure, which helps decrease the duration of forced ventilation of the lungs or do without repeated intubation of the trachea.
54例高碳酸血症(n = 14)和低氧血症(n = 40)呼吸衰竭患者采用面罩无创通气(NIVLM)。使用了美国伟康公司的鼻面罩和全面罩。通气方案个体化选择。采用触发监测通气、间歇性强制肺通气、呼气末正压辅助通气、气道双相正压通气和呼吸回路持续正压通气。NIVLM对高碳酸血症呼吸衰竭患者的有效率为100%。所有患者在NIVLM期间及停用后pCO2和ETCO2均恢复正常。尽管通气时间相对较长(229±72分钟),但患者在操作过程中未诉不适;未观察到并发症或对鼻面罩或全面罩的个体不耐受情况。在低氧血症呼吸衰竭患者中,NIVLM导致呼吸困难减轻、呼吸量增加等。NIVLM停用后检测到的变化并未消失。该组患者对鼻面罩和全面罩的个体耐受性稍差:患者抱怨鼻塞、空气不足、呼吸困难。6例患者(18.2%)出现精神运动性兴奋发作,需要镇静和镇痛治疗。总体而言,NIVLM的有效率为91%,但仅33例(87%)低氧血症患者在未再次气管插管的情况下呼吸衰竭得到缓解。该组NIVLM的平均持续时间为464±47分钟。因此,NIVLM是低氧血症和高碳酸血症呼吸衰竭患者呼吸支持的有效方法,有助于缩短强制肺通气时间或避免再次气管插管。