Aslan Y, Erduran E, Mocan H, Gedik Y, Okten A, Soylu H, Değer O
Department of Pediatrics, Karadeniz Technical University Faculty of Medicine, Trabzon, Turkey.
Turk J Pediatr. 1997 Oct-Dec;39(4):465-71.
We compared the absorption of iron from grape molasses (GM) and ferrous sulfate (FS) using the post-absorptive serum iron increase method (non-radioactive). The study involved 56 subjects, aged 6-36 months. Group I consisted of 30 subjects with iron deficiency anemia (IDA) and group II, 26 non-anemic subjects. Each group was subdivided randomly into two equal subgroups to be given either GM or FS. The absorption of the iron from GM was monitored in 15 infants with IDA and in 13 non-anemic infants, and the absorption of iron from FS was tested in the rest of the subjects in each group. In those infants in each group given GM or FS, there was no significant difference in before-test values for serum iron (SI) and total iron binding capacity (TIBC) (p > 0.05). In the group with IDA, the mean after-test SI value in FS-given infants was higher and the mean TIBC value lower than those of GM-given infants (p < 0.05). However, in the non-anemic group, there was no significant difference in the mean after-test SI and TIBC values in either GM- or FS-given infants (p > 0.05). The mean increase of serum iron in GM-given infants with IDA was 27.0 +/- 13.4 micrograms/ dl and in FS-given infants, 60.6 +/- 17.0 micrograms/dl (p < 0.05). In the non-anemic group, the mean increase of serum iron of GM-given infants was 23.0 +/- 4.3 micrograms/dl, and that of FS-given infants, 23.8 +/- 10.0 micrograms/dl (p > 0.05). We determined that in non-anemic subjects, the absorption of iron from GM was comparable to that from FS. Furthermore, we believe that grape molasses is an effective iron source in preventing iron deficiency anemia in infancy.
我们采用吸收后血清铁增加法（非放射性）比较了葡萄蜜饯（GM）和硫酸亚铁（FS）中铁的吸收情况。该研究涉及56名年龄在6至36个月的受试者。第一组由30名缺铁性贫血（IDA）受试者组成，第二组有26名非贫血受试者。每组随机分为两个相等的亚组，分别给予GM或FS。在15名IDA婴儿和13名非贫血婴儿中监测GM中铁的吸收情况，在每组其余受试者中测试FS中铁的吸收情况。在每组给予GM或FS的婴儿中，血清铁（SI）和总铁结合力（TIBC）的测试前值无显著差异（p>0.05）。在IDA组中，给予FS的婴儿测试后平均SI值较高，平均TIBC值低于给予GM的婴儿（p<0.05）。然而，在非贫血组中，给予GM或FS的婴儿测试后平均SI和TIBC值均无显著差异（p>0.05）。给予GM的IDA婴儿血清铁平均增加27.0±13.4微克/分升，给予FS的婴儿为60.6±17.0微克/分升（p<0.05）。在非贫血组中，给予GM的婴儿血清铁平均增加23.0±4.3微克/分升，给予FS的婴儿为23.8±10.0微克/分升（p>0.05）。我们确定，在非贫血受试者中，GM中铁的吸收与FS相当。此外，我们认为葡萄蜜饯是预防婴儿缺铁性贫血的有效铁源。
