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[3,5-二氧代吡唑烷系列新制剂布他酰胺与氨基比林和布他二酮相比的急性和慢性毒性研究]

[Study of the acute and chronic toxicity of a new preparation of the 3,5-dioxopyrazolidine series, butaglionamide, in comparison with amidopyrine and butadione].

作者信息

Voronkova L A, Bertash V I

出版信息

Farmakol Toksikol. 1976 Jan-Feb;39(1):98-101.

PMID:943328
Abstract

An acute and chronic toxicity of butaglionamide, a new drug in the series of 3,5-dioxopyrazolidines, was contrasted against that of amidopyrine and butadion. The data obtained testify to a much lower toxicity of butaglionamide for rats of different age, both with a single and chronic administration.

摘要

将3,5-二氧代吡唑烷系列中的一种新药布他利酰胺的急性和慢性毒性与氨基比林和布他地尼的毒性进行了对比。所获得的数据表明,无论单次给药还是长期给药,布他利酰胺对不同年龄大鼠的毒性都要低得多。

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