Leshchinskiĭ A F, Zolotareva T A, Karpenchuk O T, Zuza Z I
Farmakol Toksikol. 1979 May-Jun;42(3):265-9.
The analgetic and antipyretic action of acetylsalicylic acid is potentiated, whereas that of butadion and amidopyrine is decreased in the conditions of prior action of peloid skin applications (body temperature 42 degrees C). The effect of phenobarbital rises and that of butadion remains unchanged, whereas the inhibitory effect of ethazol revealed in the course of investigations of levelled under conditions of the action of the physical factor on the microsomal system. This leads to the changes in biotransformation and pharmacodynamics of the drugs.
在泥疗皮肤应用（体温42摄氏度）的先前作用条件下，乙酰水杨酸的镇痛和解热作用增强，而布他酮和氨基比林的作用减弱。苯巴比妥的作用增强，布他酮的作用保持不变，而在物理因素作用于微粒体系统的条件下进行的研究过程中发现，乙唑的抑制作用减弱。这导致药物的生物转化和药效学发生变化。
