Mazur N, Patterson R, Perlman D
Division of Allergy-Immunology, Northwestern University Medical School, Chicago, Illinois, USA.
Ann Allergy Asthma Immunol. 1997 Dec;79(6):546-8. doi: 10.1016/S1081-1206(10)63064-5.
Anaphylaxis is associated with IgE-mediated reactions to foods, drugs, and other allergens. Exercise-induced anaphylaxis and food plus exercise-induced anaphylaxis have been reported. Anaphylactoid reactions with no mechanisms determined have been described with radiographic contrast media. Idiopathic anaphylaxis by definition is anaphylaxis with no identifiable external allergen or stimulus. In our series of more than 350 patients with idiopathic anaphylaxis, extensive evaluation has failed to identify a cause for the anaphylaxis.
To report a first case of idiopathic anaphylaxis associated with coryzal symptoms.
A patient was evaluated for idiopathic anaphylaxis. Appropriate therapy was initiated.
The patient's anaphylactic episodes are related to the occurrence of coryzal symptoms but no clear IgE-mediated mechanism was identified.
This is the first reported association of anaphylaxis with an inciting factor of infection.
过敏反应与IgE介导的对食物、药物及其他过敏原的反应相关。运动诱发的过敏反应以及食物加运动诱发的过敏反应已有报道。对于使用放射造影剂后发生的类过敏反应，其机制尚未明确。根据定义，特发性过敏反应是指无明确外部过敏原或刺激因素的过敏反应。在我们超过350例特发性过敏反应患者的系列研究中，广泛评估未能确定过敏反应的病因。
报告首例与鼻卡他症状相关的特发性过敏反应病例。
对一名特发性过敏反应患者进行评估，并开始适当治疗。
患者的过敏发作与鼻卡他症状的出现相关，但未发现明确的IgE介导机制。
这是首次报道过敏反应与感染诱发因素之间的关联。
