Ross J A, Gurney J G
Department of Pediatrics, University of Minnesota, Minneapolis 55455, USA.
Med Pediatr Oncol. 1998 Mar;30(3):141-2. doi: 10.1002/(sici)1096-911x(199803)30:3<141::aid-mpo1>3.0.co;2-h.
There is recent evidence to suggest that extremely low birth weight is associated with the occurrence of hepatoblastoma.
In light of this possibility, we evaluated trends in hepatoblastoma incidence in the United States among children age 4 years and younger.
We found an increasing trend (5.2%) in hepatoblastoma incidence over the past two decades, a period that corresponds with improved survival of very low birth weight children.
Future studies of hepatoblastoma that incorporate birth weight are appropriate.
最近有证据表明极低出生体重与肝母细胞瘤的发生有关。
鉴于这种可能性,我们评估了美国4岁及以下儿童肝母细胞瘤发病率的趋势。
我们发现,在过去二十年中,肝母细胞瘤发病率呈上升趋势(5.2%),这一时期与极低出生体重儿童存活率的提高相对应。
纳入出生体重因素的肝母细胞瘤未来研究是合适的。