分期骨髓检查在儿童霍奇金病中的作用。
Role of staging bone marrow examination in children with Hodgkin disease.
作者信息
Mahoney D H, Schreuders L C, Gresik M V, McClain K L
机构信息
Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
出版信息
Med Pediatr Oncol. 1998 Mar;30(3):175-7. doi: 10.1002/(sici)1096-911x(199803)30:3<175::aid-mpo9>3.0.co;2-e.
PURPOSE
To determine the value of bone marrow trephine biopsy as part of the clinical staging for children presenting with Hodgkin disease.
PATIENTS AND METHODS
A retrospective study of pre-treatment bone marrow examinations was undertaken to examine the value of bone marrow staging in children with Hodgkin disease. The records of 122 children, diagnosed with Hodgkin disease at Texas Children's Hospital between February 1960 and July 1996 were reviewed. Age, sex, complete blood counts (CBC), pathology, and clinical and pathological staging results were tabulated.
RESULTS
Information was complete for analysis in 110 patients. Bone marrow trephine biopsies identified Hodgkin disease in 2/110 patients (1.8%). The patients with bone marrow disease had clinical stage IIIB disease prebiopsy. Positive bone marrow biopsy results did not effect a change in therapy, and the small number of positive cases do not allow any prediction as to prognosis.
CONCLUSION
There is no role for bone marrow trephine examination in children with clinical stage I-IIIA Hodgkin disease.
目的
确定骨髓穿刺活检作为霍奇金病患儿临床分期一部分的价值。
患者与方法
对治疗前骨髓检查进行回顾性研究，以评估骨髓分期在霍奇金病患儿中的价值。回顾了1960年2月至1996年7月在德克萨斯儿童医院确诊为霍奇金病的122例患儿的记录。将年龄、性别、全血细胞计数（CBC）、病理以及临床和病理分期结果制成表格。
结果
110例患者的信息完整可供分析。骨髓穿刺活检在110例患者中的2例（1.8%）发现了霍奇金病。骨髓受累患者在活检前临床分期为IIIB期。骨髓活检阳性结果并未影响治疗方案的改变，且阳性病例数量较少，无法对预后进行任何预测。
结论
骨髓穿刺检查对临床分期为I-IIIA期的霍奇金病患儿没有作用。
Zotero 插件