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基于双源光子束模型,使用卷积/叠加方法计算光子束放射治疗的输出因子。

Calculating output factors for photon beam radiotherapy using a convolution/superposition method based on a dual source photon beam model.

作者信息

Liu H H, Mackie T R, McCullough E C

机构信息

Division of Radiation Oncology, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA.

出版信息

Med Phys. 1997 Dec;24(12):1975-85. doi: 10.1118/1.598111.

Abstract

A realistic photon beam model based on Monte Carlo simulation of clinical linear accelerators was implemented in a convolution/superposition dose calculation algorithm. A primary and an extra-focal sources were used in this beam model to represent the direct photons from the target and the scattered photons from other head structures, respectively. The effect of the finite size of the extra-focal source was modeled by a convolution of the source fluence distribution with the collimator aperture function. Relative photon output in air (Sc) and in phantom (Scp) were computed using the convolution method with this new photon beam model. Our results showed that in a 10 MV photon beam, the Sc, Sp (phantom scatter factor), and Scp factors increased by 11%, 10%, and 22%, respectively, as the field size changed from 3 x 3 cm2 to 40 x 40 cm2. The variation of the Sc factor was contributed mostly by an increase of the extra-focal radiation with field size. The radiation backscattered into the monitor chamber inside the accelerator head affected the Sc by about 2% in the same field range. The output factors in elongated fields, asymmetric fields, and blocked fields were also investigated in this study. Our results showed that if the effect of the backscattered radiation was taken into account, output factors in these treatment fields can be predicted accurately by our convolution algorithm using the dual source photon beam model.

摘要

一种基于临床直线加速器蒙特卡罗模拟的逼真光子束模型被应用于卷积/叠加剂量计算算法中。在该束流模型中使用了一个原发射源和一个焦外源,分别代表来自靶区的直接光子和来自其他机头结构的散射光子。通过源注量分布与准直器孔径函数的卷积来模拟焦外源有限尺寸的影响。使用这种新的光子束模型,通过卷积方法计算了空气中(Sc)和模体中(Scp)的相对光子输出。我们的结果表明,在10 MV光子束中,当射野尺寸从3×3 cm2变为40×40 cm2时,Sc、Sp(模体散射因子)和Scp因子分别增加了11%、10%和22%。Sc因子的变化主要是由于焦外辐射随射野尺寸增加所致。在相同射野范围内,反向散射到加速器机头内监测电离室的辐射对Sc的影响约为2%。本研究还对拉长射野、不对称射野和遮挡射野中的输出因子进行了研究。我们的结果表明,如果考虑反向散射辐射的影响,使用双源光子束模型的卷积算法可以准确预测这些治疗射野中的输出因子。

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