Suppr超能文献

一种用于临床兆伏级X射线束卷积/叠加剂量计算的双源光子束模型。

A dual source photon beam model used in convolution/superposition dose calculations for clinical megavoltage x-ray beams.

作者信息

Liu H H, Mackie T R, McCullough E C

机构信息

Division of Radiation Oncology, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA.

出版信息

Med Phys. 1997 Dec;24(12):1960-74. doi: 10.1118/1.598110.

Abstract

A realistic model of photon beams generated by clinical linear accelerators has been incorporated in a convolution/superposition method to compute dose distributions in photon treatment fields. In this beam model, a primary photon source represents photons directly from the target, and an extra-focal photon source represents scattered photons from the primary collimator and the flattening filter. Monte Carlo simulation was used to study clinical linear accelerators producing photon beams. From the output of the Monte Carlo simulation, the fluence and spectral distributions of each photon component, as well as the geometrical characteristics of each photon source with respect to its distance to the isocenter and its source distribution, were analyzed. These quantities were used to reproduce realistic photon distributions in treatment fields, and thus to compute dose distributions using the convolution method. Our results showed that compared to the primary photon fluence, the extra-focal photon fluence from the primary collimator and the flattening filter was 11%-16% at the isocenter, among which 70% was contributed by the flattening filter. The variation of extra-focal photons in different treatment fields was predicted accurately by accounting for the finite size of the extra-focal source. Compared to measurements, dose distributions in photon treatment fields, including those of asymmetric jaw settings and at different SSDs were calculated accurately, particularly in the penumbral region, by using the convolution method with the new dual source photon beam model.

摘要

临床直线加速器产生的光子束的逼真模型已被纳入卷积/叠加方法中,以计算光子治疗野中的剂量分布。在这个束流模型中,一个初级光子源代表直接来自靶区的光子,一个焦外光子源代表来自初级准直器和平坦滤过器的散射光子。蒙特卡罗模拟用于研究产生光子束的临床直线加速器。根据蒙特卡罗模拟的输出,分析了每个光子成分的注量和能谱分布,以及每个光子源相对于其到等中心的距离和其源分布的几何特征。这些量被用于在治疗野中重现逼真的光子分布,从而使用卷积方法计算剂量分布。我们的结果表明,与初级光子注量相比,在等中心处,来自初级准直器和平坦滤过器的焦外光子注量为11%-16%,其中70%由平坦滤过器贡献。通过考虑焦外源的有限尺寸,准确预测了不同治疗野中焦外光子的变化。与测量结果相比,使用新的双源光子束模型的卷积方法准确计算了光子治疗野中的剂量分布,包括不对称准直器设置和不同源皮距处的剂量分布,特别是在半值层区域。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验