Kaneko T, Tabata S
Kazusa DNA Research Institute, Chiba, Japan.
Plant Cell Physiol. 1997 Nov;38(11):1171-6. doi: 10.1093/oxfordjournals.pcp.a029103.
Cyanobacteria are photoautotrophic organisms capable of oxygen-producing photosynthesis similar to that in eukaryotic algae and plants, and because of this, they have been used as model organisms for the study of the mechanism and regulation of oxygen-producing photosynthesis. To understand the entire genetic system in cyanobacteria, the nucleotide sequence of the entire genome of the unicellular cyanobacterium Synechocystis sp. PCC6803 has been determined. The total length of the circular genome is 3,573,470 bp, with a GC content of 47.7%. A total of 3,168 potential protein coding genes were assigned. Of these, 145 (4.6%) were identical to reported genes, and 1,259 (39.6%) and 342 (10.8%) showed similarity to reported and hypothetical genes, respectively. The remaining 1,422 (45.0%) showed no apparent similarity to any genes registered in the databases. Classification of the genes by their biological function and comparison of the gene complement with those of other organisms have revealed a variety of features of the genetic information characteristic of a photoautotrophic organism. The sequence data, as well as other information on the Synechocystis genome, is presented in CyanoBase on WWW [http:/(/)www.kazusa.or.jp/cyano/].
蓝细菌是能够进行产氧光合作用的光合自养生物，这一过程与真核藻类和植物中的产氧光合作用类似。正因如此，它们被用作研究产氧光合作用机制和调控的模式生物。为了了解蓝细菌的整个遗传系统，已测定了单细胞蓝细菌集胞藻6803（Synechocystis sp. PCC6803）全基因组的核苷酸序列。环状基因组的总长度为3,573,470碱基对，GC含量为47.7%。总共确定了3,168个潜在的蛋白质编码基因。其中，145个（4.6%）与已报道的基因相同，1,259个（39.6%）和342个（10.8%）分别与已报道的基因和假设的基因具有相似性。其余1,422个（45.0%）与数据库中登记的任何基因均无明显相似性。通过基因的生物学功能对其进行分类，并将基因互补情况与其他生物的进行比较，揭示了光合自养生物遗传信息的各种特征性特点。序列数据以及有关集胞藻基因组的其他信息可在万维网的蓝细菌数据库（CyanoBase）[http:/(/)www.kazusa.or.jp/cyano/]上获取。
