Meloen R H, Rowlands D J, Brown F
J Gen Virol. 1979 Dec;45(3):761-3. doi: 10.1099/0022-1317-45-3-761.
Antibody produced against preparations of VP1, one of the four structural polypeptides of foot-and-mouth disease virus, neutralized the virus and reacted with both full and empty particles in radioimmunoassays (RIA). Antiserum against VP2 reacted with artificial empty particles of the virus but not with full particles. In contrast, none of the individual polypeptides of poliovirus produced antisera which neutralized the virus nor reacted with it in RIA. However, antisera produced with VP1 and VP2 reacted with artificial empty particles in RIA.
针对口蹄疫病毒四种结构多肽之一的VP1制剂产生的抗体，在放射免疫分析（RIA）中中和了该病毒，并与完整颗粒和空颗粒都发生反应。抗VP2抗血清与该病毒的人工空颗粒发生反应，但不与完整颗粒发生反应。相比之下，脊髓灰质炎病毒的单个多肽产生的抗血清均不能中和该病毒，也不能在RIA中与之发生反应。然而，用VP1和VP2产生的抗血清在RIA中与人工空颗粒发生反应。
