Demircan M, Balik E
Department of Pediatric Surgery, Ege University Faculty of Medicine, Izmir, Turkey.
Pediatr Dermatol. 1997 Nov-Dec;14(6):430-2. doi: 10.1111/j.1525-1470.1997.tb00682.x.
Pilomatricoma is a skin appendage tumor that frequently involves the skin of the head, neck, and upper extremities in young children. In this prospective study, we present and discuss the characteristics of our patients with pilomatricoma. During the years 1984 to 1994, 15 children (9 girls and 6 boys) with pilomatricoma were admitted to our service. Their ages ranged from 3 to 13 years (mean age 9 years). All of the lesions of these patients were excised totally. On histopathologic examination, calcification was found in all of the specimens. No invasion or malignancy was observed by light microscopy. All patients have been followed up periodically by the same surgeons. Interestingly, we found two familial occurrences and four multiple occurrences. Although our series was too small for accurate statistical evaluation, multiple and familial occurrences of pilomatricoma (26.7% and 13.3%, respectively) were higher than in previously reported series.
毛发瘤是一种皮肤附属器肿瘤，在幼儿中常累及头、颈和上肢皮肤。在这项前瞻性研究中，我们展示并讨论了我们收治的毛发瘤患者的特征。1984年至1994年期间，15例毛发瘤患儿（9例女孩和6例男孩）入住我院。他们的年龄在3至13岁之间（平均年龄9岁）。所有患者的病变均被完全切除。经组织病理学检查，所有标本均发现钙化。光镜下未观察到浸润或恶性病变。所有患者均由同一组外科医生定期随访。有趣的是，我们发现了2例家族性发病和4例多发性发病。尽管我们的病例系列过小，无法进行准确的统计学评估，但毛发瘤的多发性和家族性发病（分别为26.7%和13.3%）高于先前报道的病例系列。
