Kishi T, Kitani M, Uegaki J, Naganuma R
Department of Psychiatry, Shimane Medical University, Izumo, Japan.
Alcohol Clin Exp Res. 1997 Dec;21(9):1730-1. doi: 10.1111/j.1530-0277.1997.tb04516.x.
Magnetic resonance imaging (MRI) of thigh and leg muscles was performed in a patient with alcoholic myopathy showing myalgia, hypercreatine kinasemia, and hypermyoglobinemia. High signal intensities in both T1- and T2-weighted images were widely distributed in the affected muscle groups, which most likely reflected lipid accumulation. Although he had hypermyoglobinemia, MRI and muscle biopsy did not show findings of rhabdomyolysis, such as necrosis, regeneration, and edema. We suggest that the high signal intensities in this case may have indicated "prerhabdomyolysis" related to alcohol abuse and that muscle MRI is useful in the evaluation of alcoholic myopathy, mainly predicting the onset of rhabdomyolysis.
对一名患有酒精性肌病、表现为肌痛、肌酸激酶血症和高肌红蛋白血症的患者进行了大腿和腿部肌肉的磁共振成像（MRI）检查。在T1加权和T2加权图像中，高信号强度广泛分布于受影响的肌肉群中，这很可能反映了脂质蓄积。尽管他有高肌红蛋白血症，但MRI和肌肉活检未显示横纹肌溶解的表现，如坏死、再生和水肿。我们认为，本例中的高信号强度可能表明与酒精滥用相关的“横纹肌溶解前期”，并且肌肉MRI在酒精性肌病的评估中有用，主要用于预测横纹肌溶解的发生。
