Reves J G, McCracken L E
Anesth Analg. 1976 Mar-Apr;55(2):235-42. doi: 10.1213/00000539-197603000-00024.
The results of this animal study confirm the induction of delayed hypersensitivity to a halothane metabolite, but the sensitization does not cause hepatic damage on subsequent halothane exposures. Before the hypothesis that hepatic necrosis following halothane has an immunologic basis can be accepted or rejected, more critical studies with different approaches must be made.
这项动物研究的结果证实了对氟烷代谢产物产生迟发型超敏反应，但这种致敏作用在后续接触氟烷时不会导致肝损伤。在关于氟烷所致肝坏死具有免疫基础这一假说被接受或否定之前，必须采用不同方法进行更严谨的研究。
