Tymchak W J, Armstrong P W
Division of Cardiology, University of Alberta, Edmonton, Canada.
Clin Lab Med. 1997 Dec;17(4):701-25.
An exciting era exists as a result of the introduction of novel markers of myocardial damage. The prognostic implications of troponins, even in the setting of "minor myocardial damage," are potentially of immense value to patient care. We need to take the next step and assess the outcomes of interventions in these settings. Use of new markers at triage will probably allow for more efficient and safe disposition of patients in this setting. There are many advantages and disadvantages to the current markers and many unanswered questions. Only through well-designed large clinical trials will we be able to realize the true potential of these markers.
由于新型心肌损伤标志物的引入，一个令人兴奋的时代已然来临。肌钙蛋白的预后意义，即使是在“轻微心肌损伤”的情况下，对患者护理也可能具有巨大价值。我们需要迈出下一步，评估在这些情况下干预措施的效果。在分诊时使用新标志物可能会使患者在这种情况下得到更高效、安全的处置。目前的标志物有诸多优缺点，还有许多未解决的问题。只有通过精心设计的大型临床试验，我们才能实现这些标志物的真正潜力。
