Suppr超能文献

癌症遗传学——基层医疗医生态度与实践调查

Cancer genetics--survey of primary care physicians' attitudes and practices.

作者信息

Friedman L C, Plon S E, Cooper H P, Weinberg A D

机构信息

Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX 77030, USA.

出版信息

J Cancer Educ. 1997 Winter;12(4):199-203. doi: 10.1080/08858199709528489.

Abstract

BACKGROUND

Genetic testing for susceptibility to cancer often involves complex medical, ethical, legal, and psychological issues that present a challenge for physicians in clinical practice.

METHODS

This study is based on survey data from 101 primary care physicians throughout Texas, measuring their interest in and attitudes about cancer genetics.

RESULTS

The majority of physicians surveyed reported that they would consider genetic screening for at least one of seven genetic disorders that predispose to cancer, and almost 20% had made one or more referrals for genetic evaluation and DNA testing. Overall, they wanted to see a variety of continuing education programs and educational materials on DNA testing for cancer susceptibility developed. Although most of the physicians accurately perceived a number of major obstacles to referring patients for genetic testing, barriers such as difficulty in interpreting test results, potential for false-positive and false-negative results, and concern about patients'reactions to test results were reported less frequently.

CONCLUSIONS

The results support other evidence for a need to provide continuing education to physicians about genetic testing for susceptibility to cancer.

摘要

背景

癌症易感性的基因检测常常涉及复杂的医学、伦理、法律和心理问题,这给临床实践中的医生带来了挑战。

方法

本研究基于得克萨斯州101名初级保健医生的调查数据,衡量他们对癌症遗传学的兴趣和态度。

结果

接受调查的大多数医生报告称,他们会考虑对至少七种易患癌症的基因疾病中的一种进行基因筛查,近20%的医生已进行了一次或多次基因评估和DNA检测的转诊。总体而言,他们希望看到针对癌症易感性DNA检测开发的各种继续教育项目和教育材料。尽管大多数医生准确地认识到将患者转诊进行基因检测存在一些主要障碍,但诸如难以解读检测结果、可能出现假阳性和假阴性结果以及担心患者对检测结果的反应等障碍的报告频率较低。

结论

这些结果支持了其他证据,即有必要为医生提供关于癌症易感性基因检测的继续教育。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验