准分子原位角膜磨镶术（LASIK）用于治疗低度、中度和高度近视。

Laser In Situ keratomileusis (LASIK) for the treatment of low moderate, and high myopia.

作者信息

Lindstrom R L, Hardten D R, Chu Y R

机构信息

Phillips Eye Institute, Minneapolis, Minnesota, USA.

出版信息

Trans Am Ophthalmol Soc. 1997;95:285-96; discussion 296-306.

PMID:9440176

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1298364/

Abstract

PURPOSE

To evaluate the efficacy, safety and predictability of LASIK in the treatment of low, moderate and high myopia.

METHODS

A perspective study of LASIK for low myopia of -0.75 to -6.00 with less than +1 D of astigmatism and for moderate and high myopia of -6.12 to -20 D with astigmatism up to +4.50 D was performed at our institution from March through November, 1996. The Chiron automated corneal shaper was used for the initial flap, and either the Summit or VISX laser was used for the refractive ablation. Preoperative refraction, uncorrected and corrected visual acuity were compared to postoperative refraction, uncorrected and corrected visual acuity. One day and 1 month results were available on all patients.

RESULTS

In the low myopia group 101 eyes underwent LASIK with a mean preoperative spherical equivalent of -4.16 +/- 1.41 D (-0.75 D to -6.00 D). Mean preoperative astigmatism was +0.4 +/- 1.29 D (0 to 0.75 D). At 1 day, 48% were 20/25 or better and 80% were 20/40 or better. The day 1 mean spherical equivalent was +0.4 +/- 0.75 D with 86% between +/- 1.00 D of emmetropia. At 1 month, 50% were 20/25 or better and 90% were 20/40 or better. The 1 month mean spherical equivalent was -0.26 +/- 0.65 D with 89% between +/- 1.00 D of emmetropia. In the high myopia group 198 eyes underwent LASIK with a preoperative mean spherical equivalent of -8.34 +/- 2.15 D)-6 to -20D) and a mean preoperative astigmatism of +1.18 +/- 0.88 D (0 to +4.5 D). At 1 day postoperatively, 17% were 20/25 or better, and 61% were 20/40 or better. The mean day one spherical equivalent was -0.26 +/- 1.56 D with 58% between +/- 1.00 D of emmetropia. At 1 month, 35% were 20/25 or better and 71% were 20/40 or better. The 1 month mean spherical equivalent was -0.28 +/- 1.18 with 63% within +/- 1.00 D of emmetropia.

CONCLUSION

Early results of using LASIK to treat low, moderate and high degrees of myopia with and without astigmatism appear promising, although longer follow-up and nomogram refinement are needed.

摘要

目的

评估准分子激光原位角膜磨镶术（LASIK）治疗低度、中度和高度近视的疗效、安全性及可预测性。

方法

1996年3月至11月在我院对-0.75至-6.00度且散光小于+1D的低度近视以及-6.12至-20度且散光达+4.50D的中度和高度近视患者进行LASIK前瞻性研究。最初的角膜瓣用Chiron自动角膜成形器制作，屈光性切削用Summit或VISX激光。比较术前验光、未矫正和矫正视力与术后验光、未矫正和矫正视力。所有患者均有术后1天和1个月的结果。

结果

低度近视组101只眼接受了LASIK手术，术前平均等效球镜度数为-4.16±1.41D（-0.75D至-6.00D）。术前平均散光为+0.4±1.29D（0至0.75D）。术后1天，48%的患者视力达到20/25或更好，80%的患者视力达到20/40或更好。术后1天平均等效球镜度数为+0.4±0.75D，86%的患者在正视眼±1.00D范围内。术后1个月，50%的患者视力达到20/25或更好，90%的患者视力达到20/40或更好。术后1个月平均等效球镜度数为-0.26±0.65D，89%的患者在正视眼±1.00D范围内。高度近视组198只眼接受了LASIK手术，术前平均等效球镜度数为-8.34±2.15D（-6至-20D），术前平均散光为+1.18±0.88D（0至+4.5D）。术后1天，17%的患者视力达到20/25或更好，61%的患者视力达到20/40或更好。术后1天平均等效球镜度数为-0.26±1.56D，58%的患者在正视眼±1.00D范围内。术后1个月，35%的患者视力达到20/25或更好，71%的患者视力达到20/40或更好。术后1个月平均等效球镜度数为-0.28±1.18D，63%的患者在正视眼±1.00D范围内。