McCord J, Borzak S
Cardiovascular Division, Henry Ford Hospital, Detroit, MI 48202, USA.
Chest. 1998 Jan;113(1):203-9. doi: 10.1378/chest.113.1.203.
Multifocal atrial tachycardia is typically seen in elderly patients with severe illnesses, most commonly COPD. The mechanism of the arrhythmia may be delayed afterdepolarizations leading to triggered activity, but this has not been firmly established. The initial treatment of multifocal atrial tachycardia should include supportive measures and aggressive reversal of precipitating causes. Since multifocal atrial tachycardia is commonly a secondary phenomenon, the role for antiarrhythmic therapy is unclear. Metoprolol, magnesium, and verapamil have been evaluated in a few treatment studies, and may have a role in the treatment of multifocal atrial tachycardia.
多源性房性心动过速通常见于患有严重疾病的老年患者，最常见于慢性阻塞性肺疾病（COPD）患者。心律失常的机制可能是延迟后除极导致触发活动，但这一点尚未得到确凿证实。多源性房性心动过速的初始治疗应包括支持性措施以及积极纠正诱发因素。由于多源性房性心动过速通常是一种继发性现象，抗心律失常治疗的作用尚不清楚。在一些治疗研究中已对美托洛尔、镁剂和维拉帕米进行了评估，它们可能在多源性房性心动过速的治疗中发挥作用。
