Kirshenbaum K J, Burke R, Fanapour F, Lapat K, Overbeeke C, Blatt D, Sukerkar A, Cavallino R P
Department of Radiology, Illinois Masonic Medical Center, Chicago 60657, USA.
J Thorac Imaging. 1998 Jan;13(1):52-7.
Fifty-six consecutive symptomatic patients with AIDS referred for gallium scintigraphy were prospectively studied with chest high-resolution computed tomography (HRCT). Results of gallium and HRCT were correlated with findings of bronchoscopy or clinical follow-up for 1 month from time of discharge. Twenty-two patients were eventually diagnosed with at least one of the following: Pneumocystis carinii, cytomegalovirus, Mycobacterium avium complex, bacteria, Kaposi's sarcoma, or lymphocytic interstitial pneumonitis. HRCT was more sensitive (82%) and more specific (91%) than gallium (59% and 75%, respectively). HRCT yielded higher positive predictive values (86%) and negative predictive values (88%) than did gallium (62% and 73%, respectively). HRCT was more helpful in guiding the method of biopsy and directing the brochoscopist to the diseased lung segment that would maximize diagnostic yield.
对连续56例因出现症状而接受镓闪烁扫描的艾滋病患者进行了前瞻性胸部高分辨率计算机断层扫描(HRCT)研究。将镓扫描和HRCT的结果与支气管镜检查结果或出院后1个月的临床随访结果进行了对比。最终,22例患者被诊断患有一种或多种以下疾病:卡氏肺孢子虫、巨细胞病毒、鸟分枝杆菌复合体、细菌、卡波西肉瘤或淋巴细胞性间质性肺炎。HRCT的敏感性(82%)和特异性(91%)均高于镓扫描(分别为59%和75%)。HRCT的阳性预测值(86%)和阴性预测值(88%)也高于镓扫描(分别为62%和73%)。HRCT在指导活检方法以及引导支气管镜检查人员找到能使诊断率最大化的患病肺段方面更有帮助。