Antoon J W, Gregg R V
Gastroenterology. 1976 May;70(5 PT.1):747-50.
It has been observed that gastric ulceration after restraint in rats is accompanied by a marked drop in body temperature. This investigation seeks to determine whether hypothermia is causally related to the restraint ulcer. Experimental animals were restrained for 18 hr while rectal temperatures were monitored with a telethermometer probe. Body temperatures of rats restrained at room temperature fell 5.0 degrees C in the first 5 hr. Gastric ulceration in this group was 100%. When body temperatures were mainatined at 38 degrees C, only 26% developed ulcers. Ulcer induction is not only accompanied by a marked temperature drop, but prevention of this phenomenon reduces the incidence of ulcers.
据观察，大鼠在受到束缚后发生胃溃疡时会伴有体温显著下降。本研究旨在确定体温过低与束缚性溃疡是否存在因果关系。实验动物被束缚18小时，同时用遥测温度计探头监测直肠温度。在室温下受到束缚的大鼠体温在前5小时内下降了5.0摄氏度。该组大鼠的胃溃疡发生率为100%。当体温维持在38摄氏度时，只有26%的大鼠发生溃疡。溃疡的诱发不仅伴随着明显的体温下降，而且防止这种现象会降低溃疡的发生率。
