Weissel M
Universitätsklinik für Innere Medizin III, Wien.
Acta Med Austriaca. 1997;24(4):154-6.
This short review summarizes the arguments for and against a screening for post-partum thyroiditis in early pregnancy: Measurement of circulating TPO (thyro-peroxydase) antibodies in early pregnancy seems a valid screening method for detecting persons at risk. TPO positive mothers seem to have, moreover, an increased risk to develop post-partial depression or symptoms of thyroid disease even without alteration of thyroid function. In addition, a higher frequency of miscarriages has been described in such patients. In contrast to these arguments in favour of performing such a screening is the fact that post-partum thyroiditis usually has only mild clinical symptoms and is a self-limiting disease.
孕早期检测循环中的甲状腺过氧化物酶(TPO)抗体似乎是一种有效的筛查方法,可用于检测有风险的人群。此外,TPO抗体阳性的母亲即使甲状腺功能未改变,发生产后抑郁症或甲状腺疾病症状的风险似乎也会增加。此外,此类患者中流产的发生率更高。与支持进行此类筛查的观点相反的是,产后甲状腺炎通常只有轻微的临床症状,且是一种自限性疾病。