Larsen F W, Mouridsen S E
Department of Child Psychiatry, Bispebjerg Hospital, Copenhagen, Denmark.
Eur Child Adolesc Psychiatry. 1997 Dec;6(4):181-90. doi: 10.1007/BF00539924.
This follow-up study reports data on 18 children fulfilling the ICD-10 criteria for childhood autism (n = 9) and Asperger syndrome (n = 9). In connection with the present study the original child psychiatric records were reassessed according to the ICD-10 criteria. The children were followed over a period of 30 years. The mean age at the time of study was 38 years. The results show that in adulthood the autistic patients had a poorer outcome than children with Asperger syndrome as regards education, employment, autonomy, marriage, reproduction and the need for continuing medical and institutional care. Particular attention is given to pharmacotherapy and the relationship between the childhood disorder and psychiatric morbidity in adult life.
这项随访研究报告了18名符合ICD - 10儿童孤独症标准（n = 9）和阿斯伯格综合征标准（n = 9）儿童的数据。在本研究中，根据ICD - 10标准对原始儿童精神病学记录进行了重新评估。这些儿童被随访了30年。研究时的平均年龄为38岁。结果显示，在成年期，自闭症患者在教育、就业、自主性、婚姻、生育以及持续医疗和机构护理需求方面的结果比阿斯伯格综合征儿童更差。特别关注了药物治疗以及儿童期疾病与成年期精神疾病发病率之间的关系。
