Frisch H, Höfer R
Klin Padiatr. 1976 Mar;188(2):104-8.
3 children aged 4, 7 and 12 years with severe thyrotoxicosis were observed. Though symptoms had existed for at least 6 months, the disease had not been diagnosed earlier; therefore clinical symptoms and diagnostic possibilities are discussed in detail. Carbimidazole was used for therapy because of the low incidence of side effects. Furthermore, an imidazole type drug allows to control underlying thyroid function during antithyroid drug therapy by measuring the 20 min. uptake (trapping). Results of long term observations are discussed.
观察了3名年龄分别为4岁、7岁和12岁的患有严重甲状腺毒症的儿童。尽管症状已存在至少6个月，但该疾病此前未被更早诊断；因此详细讨论了临床症状和诊断可能性。由于副作用发生率低，使用卡比马唑进行治疗。此外，一种咪唑类药物可通过测量20分钟摄取率（捕获率）来控制抗甲状腺药物治疗期间的基础甲状腺功能。讨论了长期观察结果。
