Suman V J, Van Winter J T, Evans M P, Simmons P S, Jacobsen S J, Manolis A L
Section of Biostatistics, Mayo Clinic Rochester, Minnesota 55905, USA.
Mayo Clin Proc. 1998 Jan;73(1):10-6. doi: 10.1016/S0025-6196(11)63613-6.
To determine which factors are associated with duration of use of a levonorgestrel implant (Norplant) for contraception in adolescents and young adults.
We retrospectively studied 144 young women (14 to 21 years of age) who chose a levonorgestrel contraceptive implant at Mayo Clinic Rochester between April 1990 and December 1993.
The following information was obtained at the time of insertion of the implant and from any follow-up visits: demographics, prior contraceptive experiences, frequency and management of complications, complications noted at removal of the implant, and subsequent contraceptive choice. The duration of use was examined.
Of the 144 young women who underwent insertion of a Norplant system, 75 telephoned or made a medical appointment because of implant-related side effects. During the follow-up period, 64 patients had the Norplant system removed. The Kaplan-Meier estimate of the probability of the Norplant system remaining in place for at least 12 months was 83 % and for at least 24 months was 63 %. Duration of Norplant use was not found to differ with respect to age, prior contraceptive use, or timing of insertion, but it was significantly shorter among those with a prior pregnancy than in those who had never been pregnant.
These findings suggest that a group of young women who are likely to continue use of a contraceptive implant (with or without treatment for side effects) are those who have never been pregnant.
确定哪些因素与青少年及年轻女性使用左炔诺孕酮宫内节育系统(Norplant)进行避孕的使用时长相关。
我们回顾性研究了1990年4月至1993年12月期间在罗切斯特梅奥诊所选择左炔诺孕酮避孕植入物的144名年轻女性(14至21岁)。
在植入时及任何后续随访中获取以下信息:人口统计学资料、既往避孕经历、并发症的发生频率及处理情况、取出植入物时发现的并发症以及后续的避孕选择。对使用时长进行了检查。
在144名接受Norplant系统植入的年轻女性中,75人因与植入物相关的副作用致电或预约就诊。在随访期间,64名患者取出了Norplant系统。Norplant系统至少保留12个月的概率的Kaplan-Meier估计值为83%,至少保留24个月的概率为63%。未发现Norplant的使用时长在年龄、既往避孕使用情况或植入时间方面存在差异,但既往有过妊娠的女性的使用时长显著短于从未怀孕的女性。
这些发现表明,一组可能会持续使用避孕植入物(无论是否接受副作用治疗)的年轻女性是那些从未怀孕的女性。