Majerus P W
Washington University School of Medicine, Division of Hematology, 660 S. Euclid Avenue, Campus Box 8125, St Louis, Missouri 63110-1093, USA.
Curr Biol. 1998 Jan 29;8(3):R87-9. doi: 10.1016/s0960-9822(98)70053-3.
Cyclooxygenase catalyses a key step in prostaglandin biosynthesis, and recent work suggests that one isoenzyme, COX-2, has important roles in early stages of pregnancy; it also appears to be involved in the somewhat analogous process of colon tumor formation and spread.
环氧化酶催化前列腺素生物合成中的关键步骤,最近的研究表明,一种同工酶COX - 2在妊娠早期具有重要作用;它似乎也参与了在某些方面与之类似的结肠肿瘤形成和扩散过程。