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糖尿病中的β-血小板球蛋白和糖化血红蛋白

Beta thromboglobulin and glycosylated haemoglobin in diabetes mellitus.

作者信息

Matthews J H, O'Connor J F, Hearnshaw J R, Wood J K

出版信息

Scand J Haematol. 1979 Nov;23(5):421-6. doi: 10.1111/j.1600-0609.1979.tb02743.x.

DOI:10.1111/j.1600-0609.1979.tb02743.x
PMID:94458
Abstract

No correlation has been demonstrated between the elevated levels of plasma beta-thromboglobulin and glycosylated haemoglobin found in a group of 97 diabetic patients. The abnormality in diabetic platelets which is reflected by beta-thromboglobulin levels may not therefore be a direct result of poor metabolic control. The highest levels of beta-thromboglobulin were found in those patients with a raised blood urea. Glycosylated haemoglobin levels correlated with prevailing blood glucose and with the type of therapy employed, and were highest in the insulin dependent diabetics, intermediate in those on tablets and lowest in those on diet alone.

摘要

在一组97名糖尿病患者中,血浆β-血小板球蛋白水平升高与糖化血红蛋白之间未显示出相关性。因此,由β-血小板球蛋白水平反映出的糖尿病血小板异常可能并非代谢控制不佳的直接结果。血尿素升高的患者β-血小板球蛋白水平最高。糖化血红蛋白水平与当时的血糖水平及所采用的治疗方式相关,在胰岛素依赖型糖尿病患者中最高,在服用片剂治疗的患者中处于中等水平,而在仅采用饮食治疗的患者中最低。

相似文献

1
Beta thromboglobulin and glycosylated haemoglobin in diabetes mellitus.糖尿病中的β-血小板球蛋白和糖化血红蛋白
Scand J Haematol. 1979 Nov;23(5):421-6. doi: 10.1111/j.1600-0609.1979.tb02743.x.
2
Factors affecting plasma beta-thromboglobulin in diabetes mellitus.影响糖尿病患者血浆β-血小板球蛋白的因素
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Plasma beta-thromboglobulin in diabetics with and without microangiopathic complications.患有和未患有微血管病变并发症的糖尿病患者的血浆β-血小板球蛋白
Diabetologia. 1981 Aug;21(2):160-1. doi: 10.1007/BF00251286.
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引用本文的文献

1
A study of platelet-relevant parameters in patients with diabetic microangiopathy.
Diabetologia. 1983 Jul;25(1):21-5. doi: 10.1007/BF00251891.
2
Relationships between metabolic and hemostatic variables in uncomplicated diabetes.单纯性糖尿病患者代谢与止血变量之间的关系。
Acta Diabetol Lat. 1981 Jul-Sep;18(3):199-206. doi: 10.1007/BF02047890.
3
Beta-thromboglobulin and fibrinopeptide A in diabetes mellitus as markers of vascular damage.糖尿病中的β-血小板球蛋白和纤维蛋白肽A作为血管损伤的标志物。
Acta Diabetol Lat. 1985 Jan-Mar;22(1):39-45. doi: 10.1007/BF02591091.