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糖尿病中的β-血小板球蛋白和糖化血红蛋白

Beta thromboglobulin and glycosylated haemoglobin in diabetes mellitus.

作者信息

Matthews J H, O'Connor J F, Hearnshaw J R, Wood J K

出版信息

Scand J Haematol. 1979 Nov;23(5):421-6. doi: 10.1111/j.1600-0609.1979.tb02743.x.

Abstract

No correlation has been demonstrated between the elevated levels of plasma beta-thromboglobulin and glycosylated haemoglobin found in a group of 97 diabetic patients. The abnormality in diabetic platelets which is reflected by beta-thromboglobulin levels may not therefore be a direct result of poor metabolic control. The highest levels of beta-thromboglobulin were found in those patients with a raised blood urea. Glycosylated haemoglobin levels correlated with prevailing blood glucose and with the type of therapy employed, and were highest in the insulin dependent diabetics, intermediate in those on tablets and lowest in those on diet alone.

摘要

在一组97名糖尿病患者中,血浆β-血小板球蛋白水平升高与糖化血红蛋白之间未显示出相关性。因此,由β-血小板球蛋白水平反映出的糖尿病血小板异常可能并非代谢控制不佳的直接结果。血尿素升高的患者β-血小板球蛋白水平最高。糖化血红蛋白水平与当时的血糖水平及所采用的治疗方式相关,在胰岛素依赖型糖尿病患者中最高,在服用片剂治疗的患者中处于中等水平,而在仅采用饮食治疗的患者中最低。

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