与运动性痉挛和横纹肌溶解相关的肌丝源性圆柱状螺旋结构。
Cylindrical spirals of myofilamentous origin associated with exertional cramps and rhabdomyolysis.
作者信息
Wolfe G I, Burns D K, Krampitz D, Barohn R J
机构信息
Department of Neurology, University of Texas Southwestern Medical Center, Dallas 75235-8897, USA.
出版信息
Neuromuscul Disord. 1997 Dec;7(8):536-8. doi: 10.1016/s0960-8966(97)00101-6.
We describe the presence of cylindrical spirals on muscle biopsy from a 31-year-old man who developed rhabodomyolysis following a long run. He had a prior history of exertional cramps and myoglobinuria. His maternal grandfather had similar symptoms. Transmission electron micrographs demonstrated continuity between the lamellae of the cylindrical spirals and native myofilaments. Whether these unusual structures confer a derangement in myofilament function is uncertain.
我们描述了一名31岁男性肌肉活检中出现的圆柱形螺旋结构，该男性在长跑后发生了横纹肌溶解。他既往有运动性痉挛和肌红蛋白尿病史。他的外祖父有类似症状。透射电子显微镜照片显示圆柱形螺旋结构的薄片与天然肌丝之间存在连续性。这些异常结构是否会导致肌丝功能紊乱尚不确定。
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