Kiper D C, Fenstemaker S B, Gegenfurtner K R
Howard Hughes Medical Institute, New York University, New York, USA.
Vis Neurosci. 1997 Nov-Dec;14(6):1061-72. doi: 10.1017/s0952523800011779.
We recorded from single cells in area V2 of cynomolgus monkeys using standard acute recording techniques. After measuring each cell's spatial and temporal properties, we performed several tests of its chromatic properties using sine-wave gratings modulated around a mean gray background. Most cells behaved like neurons in area V1 and their responses were adequately described by a model that assumes a linear combination of cone signals. Unlike in V1, we found a subpopulation of cells whose activity was increased or inhibited by stimuli within a narrow range of color combinations. No particular color directions were preferentially represented. V2 cells showing color specificity, including cells showing narrow chromatic tuning, were present in any of the stripe compartments, as defined by cytochrome-oxidase (CO) staining. An addition of chromatic contrast facilitated the responses of most neurons to gratings with various luminance contrasts. Neurons in all three CO compartments gave significant responses to isoluminant gratings. Receptive-field properties of cells were generally similar for luminance and chromatically defined stimuli. We found only a small number of cells with a clearly identifiable double-opponent receptive-field organization.
我们使用标准急性记录技术从食蟹猴的V2区单个细胞进行记录。在测量每个细胞的空间和时间特性后，我们使用围绕平均灰色背景调制的正弦波光栅对其颜色特性进行了多项测试。大多数细胞的行为类似于V1区的神经元，其反应可以通过一个假设视锥信号线性组合的模型得到充分描述。与V1区不同，我们发现了一个细胞亚群，其活动在狭窄的颜色组合范围内会被刺激增强或抑制。没有特定的颜色方向被优先表示。如细胞色素氧化酶（CO）染色所定义的，显示颜色特异性的V2细胞，包括显示狭窄颜色调谐的细胞，存在于任何条纹区隔中。增加颜色对比度促进了大多数神经元对具有各种亮度对比度的光栅的反应。所有三个CO区隔中的神经元对等亮度光栅都有显著反应。对于亮度和颜色定义的刺激，细胞的感受野特性通常相似。我们只发现了少数具有清晰可识别的双拮抗感受野组织的细胞。
